A breakthrough in cardiovascular disease diagnosis: Endomyocardial biopsy
The University of Medicine and Pharmacy Hospital Ho Chi Minh City (BV ĐHYD) has recently implemented an advanced technique in the cardiovascular field – endomyocardial biopsy. This method enables early and accurate detection of myocardial diseases, and also plays an important role in monitoring patients after heart transplantation.
According to Dr. Vũ Hoàng Vũ, PhD – Head of the Interventional Cardiology Department at BV ĐHYD, endomyocardial biopsy is a particularly useful tool for identifying the cause of unexplained heart failure, as well as assessing the extent of myocardial damage in complex diseases. Obtaining a small tissue sample from the heart allows physicians not only to diagnose accurately but also to determine a more appropriate treatment plan for each specific case.
Dr. Nguyễn Xuân Vinh – Interventional Cardiology Department at BV ĐHYD, stated that this technique is especially important for monitoring patients after heart transplantation. By directly collecting tissue samples from the heart, doctors can detect early signs of graft rejection, thereby adjusting treatment regimens promptly to protect the function of the transplanted heart. Moreover, endomyocardial biopsy also helps identify rare cardiac conditions such as giant cell myocarditis or amyloidosis – conditions that are difficult to detect with conventional imaging diagnostics.

The procedure for performing an endomyocardial biopsy is meticulously prepared, ensuring absolute safety for the patient. Doctors will access the heart chambers via the veins, using a specialized instrument to obtain small tissue samples from the heart muscle under the guidance of modern imaging devices. The entire technique is carried out in the catheterization lab, with seamless coordination among specialist physicians, nurses, and technicians.
Provides many important benefits
Although it is an invasive technique, endomyocardial biopsy offers significant clinical advantages. At DHYD Hospital, this process is performed under strict control, from indication assessment to post‑procedure monitoring. This helps minimize possible complications such as bleeding, arrhythmia, or valve injury.
According to cardiology specialist 2 Âu Thanh Tùng - Head of Integrated Planning Department, the application of endomyocardial biopsy has opened many new opportunities in the diagnosis and treatment of cardiovascular diseases. For patients after heart transplantation, this technique helps detect early signs of graft rejection, allowing timely intervention. In cases of unexplained heart failure, obtaining myocardial tissue samples enables doctors to precisely determine the nature of the lesion, helping to personalize treatment protocols and optimize outcomes.
It is not only a diagnostic method; endomyocardial biopsy is also a significant advancement in the field of interventional cardiology. With clear practical applications, it promises to be a method that brings many long‑term benefits to patients, helping to improve the quality of cardiovascular health care in Vietnam.
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